Neutrophils / HDL Ratio (NHR)

A research-based ratio linking inflammation (neutrophils) with heart-protective HDL to add context to overall risk.

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Test Summary

Sample Type 
Blood
Required Blood
Analysis Type
Serum and whole blood
Collection method
In person at the lab; at-home where available

Why test

Neutrophils / HDL Ratio (NHR)

?

Clinicians may review NHR alongside your lipid panel and complete blood count to add context on inflammation and heart health. It can help frame lifestyle focus and whether to look deeper at cardiometabolic or inflammatory patterns. This marker supports conversations; it is not guideline-endorsed and is best used for trends rather than one-off decisions. You can test this marker with Aniva across Germany and Finland.

What is

Neutrophils / HDL Ratio (NHR)

?

Clinicians may review NHR alongside your lipid panel and complete blood count to add context on inflammation and heart health. It can help frame lifestyle focus and whether to look deeper at cardiometabolic or inflammatory patterns. This marker supports conversations; it is not guideline-endorsed and is best used for trends rather than one-off decisions. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Neutrophils / HDL Ratio (NHR)

?

High: May suggest higher inflammatory burden and/or lower HDL protection. In research, higher values can align with less favorable cardiometabolic profiles; consider repeating when well and reviewing lifestyle, medications, and related labs.
Low: May reflect lower inflammation and/or higher HDL levels. Use alongside other markers to confirm a favorable pattern. This marker is not guideline-endorsed; no standardized cutoffs. Prioritize trends and clinical context over single values.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Morning; when you are well, not acutely ill
  • Collection: In person at the lab; at-home where available
  • Typical volume:
  • Analysis: Serum for HDL; whole blood (EDTA) for neutrophils
  • Prep tips: Hydrate; avoid heavy exercise and alcohol for 24 hours; share medications
  • Turnaround: 1–3 working days

Track your

Neutrophils / HDL Ratio (NHR)

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Neutrophils / HDL Ratio (NHR)
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Limits & interferences with

Neutrophils / HDL Ratio (NHR)

:

Common factors that can skew results include acute infections or fever, recent surgery, corticosteroids or stress hormones, smoking or vaping, heavy alcohol intake, strenuous exercise, dehydration, and pregnancy. Meals have little effect on HDL, but very high-fat meals and alcohol can nudge values. Some medicines (statins, niacin, fibrates) also influence lipids.

Special situations (when to confirm or adjust): after an illness, flare, vaccination, or surgery, repeat when recovered to avoid transient changes.

Questions about

Neutrophils / HDL Ratio (NHR)

:

What does a high or low NHR mean? A higher ratio may point to more inflammation or lower HDL protection. A lower ratio may align with a more favorable pattern, but context matters.

Do I need to fast for this test? Fasting is not required. Non‑fasting HDL and a routine blood count are generally acceptable.

How often should I check it? Many people repeat it with routine blood work or after lifestyle changes. Discuss timing with your clinician if you’ve been ill recently.

What can affect my result? Recent infections, steroids, smoking, heavy alcohol, hard workouts, dehydration, and pregnancy can shift values. Share all medicines and supplements.

How long until results are ready? Most labs return results in about 1–3 working days.

What should I discuss with my clinician? Review trends alongside your CBC, lipid panel, blood pressure, and history. Ask whether any changes are needed or if a recheck is best.

Sources:

  • MedlinePlus — HDL Cholesterol Test. (2024). https://medlineplus.gov/lab-tests/hdl-cholesterol-test/
  • MedlinePlus — Absolute Neutrophil Count (ANC). (2024). https://medlineplus.gov/lab-tests/absolute-neutrophil-count-anc/
  • CDC — Cholesterol: Testing and Results. (2024). https://www.cdc.gov/cholesterol/testing.htm
  • EAS/ESC — Fasting not routinely required for lipid profile. (2016). https://academic.oup.com/eurheartj/article/37/25/1944/1748921
  • ARUP Consult — Complete Blood Count. (2023). https://arupconsult.com/content/complete-blood-count
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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