High-Sensitivity C-Reactive Protein (hs-CRP)

A highly sensitive blood test that reflects low-grade inflammation and helps refine heart risk.

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High-Sensitivity C-Reactive Protein (hs-CRP)
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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

High-Sensitivity C-Reactive Protein (hs-CRP)

?

hs-CRP helps estimate low-grade inflammation that can refine your heart risk, especially when overall risk is borderline. Clinicians use it to track trends over time and to support prevention talks about lifestyle or statin therapy. Testing is most useful when you feel well, since infections and injuries can briefly spike levels. You can test this marker with Aniva across Germany and Finland.

What is

High-Sensitivity C-Reactive Protein (hs-CRP)

?

hs-CRP helps estimate low-grade inflammation that can refine your heart risk, especially when overall risk is borderline. Clinicians use it to track trends over time and to support prevention talks about lifestyle or statin therapy. Testing is most useful when you feel well, since infections and injuries can briefly spike levels. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

High-Sensitivity C-Reactive Protein (hs-CRP)

?

High: Points to more ongoing inflammation; if you’re well, it may suggest higher cardiovascular risk. Consider checking lipids and risk factors, and recheck in a few weeks.
Low: Suggests little ongoing inflammation and a lower inflammatory burden. Stable, low values over time are reassuring. If you recently had a cold, vaccine, or hard workout, wait 2–3 weeks and test again.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: When healthy; delay if you have a cold, fever, or injury
  • Collection: In person at the lab; at-home where available
  • Typical volume: 1 mL
  • Analysis: Serum; high-sensitivity immunoassay
  • Prep tips: Avoid intense exercise and alcohol for 24 hours; keep meds and supplements consistent
  • Turnaround: 1–3 business days

High-Sensitivity C-Reactive Protein (hs-CRP)

is best interpreted with:

Track your

High-Sensitivity C-Reactive Protein (hs-CRP)

with Aniva

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Book your 
High-Sensitivity C-Reactive Protein (hs-CRP)
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Limits & interferences with

High-Sensitivity C-Reactive Protein (hs-CRP)

:

Common factors that can skew hs-CRP include a cold or flu, recent vaccination, injury, surgery, dental work, strenuous exercise, smoking, obesity, poor sleep, and pregnancy. Some medicines may lower levels (statins, NSAIDs, corticosteroids), while others can raise them (estrogen therapy). Minor day-to-day variation occurs; test when you’re well and try to use similar timing.

Special situations (when to confirm or adjust): repeat 2–3 weeks after acute illness, flare, procedure, or vaccination; discuss timing if pregnant or living with chronic inflammatory disease.

Questions about

High-Sensitivity C-Reactive Protein (hs-CRP)

:

What does an hs-CRP result mean? It reflects the level of low-grade inflammation in your body. Higher values suggest more inflammation and may signal higher heart risk.

Do I need to fast for hs-CRP? No. Fasting is not required. Testing when you’re well gives the most useful result.

What can affect my result? Illness, recent vaccination, injury, hard workouts, smoking, pregnancy, and some medicines can raise or lower hs-CRP.

How often should I test? Many people repeat it in 2–3 weeks if elevated, or every 3–12 months to track trends, based on clinician advice.

How long do results take? Most labs report hs-CRP within 1–3 business days.

What should I discuss with my clinician? Share any recent illness, exercise, or new medicines, and review your overall heart risk and next steps.

Sources:

  • ACC/AHA — 2019 Guideline on the Primary Prevention of Cardiovascular Disease. (2019). https://www.ahajournals.org/doi/10.1161/CIR.0000000000000678
  • ACC/AHA — 2018 Guideline on the Management of Blood Cholesterol. (2018). https://www.ahajournals.org/doi/10.1161/CIR.0000000000000625
  • MedlinePlus — C-reactive protein (CRP) test. (2024). https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/
  • ARUP Consult — High-Sensitivity C-Reactive Protein. (2024). https://arupconsult.com/content/high-sensitivity-c-reactive-protein
  • Mayo Clinic — C-reactive protein test. (2023). https://www.mayoclinic.org/tests-procedures/c-reactive-protein/about/pac-20385228
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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