Urea/Creatinine Ratio

Compares urea and creatinine to give quick context on kidney health and hydration.

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Urea/Creatinine Ratio
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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

Urea/Creatinine Ratio

?

Clinicians order this ratio to help explain unusual urea or creatinine results and to assess hydration or blood flow to the kidneys. It can offer clues in suspected dehydration, gastrointestinal bleeding, high protein intake, or sudden kidney stress. Results often guide next steps like repeating the test, reviewing medicines and diet, or adding eGFR and urinalysis. You can test this marker with Aniva across Germany and Finland.

What is

Urea/Creatinine Ratio

?

Clinicians order this ratio to help explain unusual urea or creatinine results and to assess hydration or blood flow to the kidneys. It can offer clues in suspected dehydration, gastrointestinal bleeding, high protein intake, or sudden kidney stress. Results often guide next steps like repeating the test, reviewing medicines and diet, or adding eGFR and urinalysis. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Urea/Creatinine Ratio

?

High: Often reflects dehydration or reduced kidney blood flow; can also rise with high protein intake, tissue breakdown, upper GI bleeding, or certain medicines.
Low: May reflect low protein intake or reduced urea production (such as with advanced liver disease), or relatively higher creatinine from larger muscle mass, recent hard exercise, or creatine supplements. This ratio is not guideline-endorsed; no standardized cutoffs. Trends and context with other tests matter most.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Morning, when well hydrated
  • Collection: Venipuncture
  • Typical volume: 1 mL
  • Analysis: Serum
  • Prep tips: Drink water as usual; avoid heavy exercise 24 hours; list medicines and supplements
  • Turnaround: 1–3 business days

Urea/Creatinine Ratio

is best interpreted with:

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Urea/Creatinine Ratio

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Urea/Creatinine Ratio
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Limits & interferences with

Urea/Creatinine Ratio

:

Common factors include dehydration or overhydration, high-protein meals, gastrointestinal bleeding, recent strenuous exercise, and pregnancy. Certain medicines (like corticosteroids or some antibiotics) and supplements (such as creatine or high-dose vitamin C) can shift the ratio. Muscle mass, acute illness, and timing of sampling may also affect results.

Special situations (when to confirm or adjust): acute illness, pregnancy, extremes of age or muscle mass, or known liver disease—repeat and interpret with related kidney tests.

Questions about

Urea/Creatinine Ratio

:

What do my results mean? A higher ratio often points to dehydration or more urea production; a lower ratio may reflect low protein intake or reduced urea production. Your clinician will interpret it with other tests.

Do I need to fast? No. Fasting is not required for this test.

What can affect the ratio? Hydration, high-protein diet, creatine supplements, recent hard exercise, pregnancy, and some medicines can shift results.

How often should I test it? It’s usually checked when kidney results change or during follow-up. Your clinician will advise the timing.

How long do results take? Most labs report results within 1–3 business days.

What should I discuss with my clinician? Share your medications, supplements, hydration, recent illness, and whether you need eGFR or a urinalysis for context.

Sources:

  • MedlinePlus — BUN (Blood Urea Nitrogen) Test. (2024). https://medlineplus.gov/lab-tests/bun-blood-urea-nitrogen-test/
  • MedlinePlus — Creatinine Test. (2024). https://medlineplus.gov/lab-tests/creatinine-test/
  • ARUP Consult — Acute Kidney Injury. (2024). https://arupconsult.com/content/acute-kidney-injury
  • NIDDK — Estimating Glomerular Filtration Rate (eGFR). (2024). https://www.niddk.nih.gov/health-information/diagnostic-tests/egfr
  • Cleveland Clinic — BUN/Creatinine Ratio: What It Is and What It Means. (2023). https://my.clevelandclinic.org/health/diagnostics/22850-bun-creatinine-ratio
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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