Aspartate Aminotransferase (AST)

AST is an enzyme blood test that helps check liver and muscle health.

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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

Aspartate Aminotransferase (AST)

?

Clinicians order AST to look for liver stress or injury and to monitor known liver conditions. It can also rise with muscle injury or after certain medicines or supplements. Results guide next steps, like repeating the test, reviewing medications, or adding a full liver panel. You can test this marker with Aniva across Germany and Finland.

What is

Aspartate Aminotransferase (AST)

?

Clinicians order AST to look for liver stress or injury and to monitor known liver conditions. It can also rise with muscle injury or after certain medicines or supplements. Results guide next steps, like repeating the test, reviewing medications, or adding a full liver panel. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Aspartate Aminotransferase (AST)

?

High: May signal liver cell irritation or injury; can also rise after hard exercise, muscle injury, alcohol use, or some medicines and supplements.
Low: Usually not concerning; sometimes seen in pregnancy or with low vitamin B6, but rarely needs action alone. If elevated, avoid heavy workouts and alcohol, review medicines, and consider repeating with a full liver panel.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Any time; avoid strenuous exercise 24–48 hours before, if possible
  • Collection: Venous blood draw
  • Typical volume: 1 mL
  • Analysis: Serum chemistry (enzymatic rate method)
  • Prep tips: Tell your clinician about medicines, alcohol, and supplements; stay hydrated; rest before testing
  • Turnaround: 1–2 business days

Aspartate Aminotransferase (AST)

is best interpreted with:

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Aspartate Aminotransferase (AST)

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Aspartate Aminotransferase (AST)
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Limits & interferences with

Aspartate Aminotransferase (AST)

:

Common factors that can affect AST include recent strenuous exercise, muscle injury, intramuscular shots, alcohol within 24–48 hours, and some medicines (for example statins, acetaminophen, anti-seizure drugs, certain antibiotics and antifungals). Herbal products like kava or comfrey and high-dose niacin may raise levels. Acute illness, dehydration, and sample hemolysis (breaking red cells during the blood draw) can also shift results. Pregnancy can lower AST slightly. For the most stable reading, test when you’re well and at rest.

Special situations: If results are unexpected, confirm with a repeat test and a full liver panel (ALT, ALP, bilirubin, GGT), especially after hard exercise, alcohol use, or new medicines.

Questions about

Aspartate Aminotransferase (AST)

:

What does an AST result mean in plain terms? It shows how much of this enzyme is in your blood. Higher levels can reflect liver or muscle stress and guide next steps.

Do I need to fast for an AST test? No. Fasting is not required for AST. Testing at rest gives the most stable result.

What can temporarily raise AST? Hard workouts, muscle injury, alcohol, and some medicines or supplements can raise AST for a short time.

How often should I test AST? Your clinician may repeat it in weeks to confirm changes, or monitor it regularly if you take liver‑affecting medicines.

How long do results take? Most labs report AST within 1–2 business days.

What should I discuss with my clinician? Share your medicines, supplements, alcohol use, recent exercise, and any symptoms. Ask if more liver tests are needed.

Sources:

  • MedlinePlus — Aspartate aminotransferase (AST) test. (2024). https://medlineplus.gov/lab-tests/aspartate-aminotransferase-ast-test/
  • AASLD — How to approach elevated liver enzymes. (2023). https://www.aasld.org/liver-fellow-network/core-series/how-approach-elevated-liver-enzymes
  • ACG — Evaluation of Abnormal Liver Chemistries. (2017). https://gi.org/clinical-guidelines/evaluation-of-abnormal-liver-chemistries/
  • ARUP Consult — Liver Disease Evaluation. (2024). https://arupconsult.com/content/liver-disease-evaluation
  • Mayo Clinic Laboratories — Aspartate Aminotransferase (AST), Serum. (2023). https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/8428
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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