hs-CRP / Ferritin Ratio

A context ratio comparing inflammation (hs-CRP) to iron storage (ferritin) to clarify results.

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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

hs-CRP / Ferritin Ratio

?

This ratio can help show whether inflammation might be influencing ferritin, which also rises during illness. It’s sometimes used to add context when exploring fatigue, low energy, or anemia-like symptoms, or when tracking recovery from inflammation. It can guide follow-up testing, such as a full iron panel or repeat testing when you’re well. You can test this marker with Aniva across Germany and Finland.

What is

hs-CRP / Ferritin Ratio

?

This ratio can help show whether inflammation might be influencing ferritin, which also rises during illness. It’s sometimes used to add context when exploring fatigue, low energy, or anemia-like symptoms, or when tracking recovery from inflammation. It can guide follow-up testing, such as a full iron panel or repeat testing when you’re well. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

hs-CRP / Ferritin Ratio

?

High: Inflammation appears high relative to iron stores. Ferritin may be influenced by illness; consider retesting when well and reviewing an iron panel.
Low: Inflammation appears low relative to ferritin. Ferritin may better reflect iron stores; trends and clinical context still matter. This ratio is not guideline-endorsed; no standardized cutoffs.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: When you are well; avoid testing during acute illness
  • Collection: Venous blood draw
  • Typical volume: 1 mL
  • Analysis: Serum
  • Prep tips: Avoid vigorous exercise and alcohol 24 hours before; stay hydrated
  • Turnaround: 1–3 business days

hs-CRP / Ferritin Ratio

is best interpreted with:

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hs-CRP / Ferritin Ratio

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Limits & interferences with

hs-CRP / Ferritin Ratio

:

Common factors that can skew results include recent infections, injuries, or vaccinations, which can raise hs-CRP. Intense exercise, poor sleep, smoking, and obesity may also elevate hs-CRP. Iron supplements, recent infusions, and vitamin C can influence iron studies and ferritin. Anti-inflammatory medicines (like NSAIDs or steroids) and statins may lower CRP. Pregnancy and chronic inflammatory conditions can increase ferritin independent of iron stores.

Special situations: confirm or adjust interpretation if you are acutely ill, postpartum, recently had surgery, on anti-inflammatory therapy, or living with chronic inflammation.

Questions about

hs-CRP / Ferritin Ratio

:

What does a higher or lower ratio mean? A higher ratio suggests inflammation may be affecting ferritin. A lower ratio suggests ferritin may reflect iron stores more directly.

Do I need to fast? No. Fasting does not meaningfully change hs-CRP or ferritin for this ratio.

What can affect the result? Recent illness, hard workouts, smoking, pregnancy, iron supplements, and anti-inflammatory medicines can shift values. Test when you feel well if possible.

How often should I test? Many people repeat testing after recovery from illness or after changing supplements or lifestyle. Your clinician can suggest a timeframe.

How long do results take? Most labs report hs-CRP and ferritin within 1–3 business days.

What should I discuss with my clinician? Review symptoms, diet, supplements, and medicines. Ask whether to add an iron panel or repeat testing when you are well.

Sources:

  • WHO — Use of ferritin concentrations to assess iron status in individuals and populations. (2020). https://www.who.int/publications/i/item/9789240000124
  • ARUP Consult — Iron Deficiency Anemia Testing. (2024). https://arupconsult.com/content/iron-deficiency-anemia
  • MedlinePlus — Ferritin blood test. (2024). https://medlineplus.gov/lab-tests/ferritin-blood-test/
  • MedlinePlus — C-reactive protein (CRP) test. (2024). https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/
  • Mayo Clinic — C-reactive protein (CRP) test. (2023). https://www.mayoclinic.org/tests-procedures/c-reactive-protein/about/pac-20385228
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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