Gamma-Glutamyl Transferase (GGT)

GGT is a liver enzyme that helps flag bile duct stress and alcohol-related effects.

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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

Gamma-Glutamyl Transferase (GGT)

?

Clinicians order GGT to help explain abnormal liver tests, especially when alkaline phosphatase is high. It helps check bile duct flow, medication effects, or alcohol exposure. Results can guide next steps like repeat testing, imaging, or reviewing medicines and alcohol use. You can test this marker with Aniva across Germany and Finland.

What is

Gamma-Glutamyl Transferase (GGT)

?

Clinicians order GGT to help explain abnormal liver tests, especially when alkaline phosphatase is high. It helps check bile duct flow, medication effects, or alcohol exposure. Results can guide next steps like repeat testing, imaging, or reviewing medicines and alcohol use. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Gamma-Glutamyl Transferase (GGT)

?

High: May point to bile duct irritation or blockage, alcohol use, or medicines that stimulate liver enzymes. When alkaline phosphatase is also high, an elevated GGT supports a liver or bile duct source. Tracking trends helps; avoiding alcohol and reviewing medicines with your clinician may lower levels.
Low: Usually not concerning and rarely used for decisions. Persistently low values typically do not need further workup.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Any time; avoid heavy alcohol for 24–48 hours if possible
  • Collection: Venous blood draw
  • Typical volume: 1 mL
  • Analysis: Serum
  • Prep tips: Avoid alcohol for 24–48 hours; share all medicines and supplements; avoid strenuous exercise the day before
  • Turnaround: 1–3 working days

Gamma-Glutamyl Transferase (GGT)

is best interpreted with:

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Gamma-Glutamyl Transferase (GGT)

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Gamma-Glutamyl Transferase (GGT)
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Limits & interferences with

Gamma-Glutamyl Transferase (GGT)

:

Common factors that can change GGT include recent alcohol use, smoking, and some medicines (for example, anti-seizure drugs, rifampin, and certain herbal supplements). Levels can also rise with obesity, diabetes, thyroid problems, heart failure, acute illness, or recent surgery. GGT tends to be higher in men and increases with age; pregnancy may lower it.

Special situations: confirm or adjust interpretation during pregnancy, within weeks after stopping heavy drinking, in children, or when taking enzyme‑inducing medicines.

Questions about

Gamma-Glutamyl Transferase (GGT)

:

What does a high GGT mean? It often signals bile duct irritation, liver stress, alcohol effects, or medicine effects. Your clinician will review it with other liver tests.

Do I need to fast for a GGT test? No. You do not need to fast, but avoiding alcohol before the test is helpful.

What can raise GGT besides liver disease? Alcohol, smoking, certain medicines, obesity, diabetes, thyroid issues, and recent illness can raise GGT.

How often should I test GGT? It depends on your situation. Many people recheck after changing alcohol use, medicines, or when other liver tests are abnormal.

How long do results take? Most labs report results in 1–3 working days.

What should I discuss with my clinician? Share symptoms, all medicines and supplements, alcohol use, and results of other liver tests like ALT, AST, ALP, and bilirubin.

Sources:

  • American Association for the Study of Liver Diseases — Evaluation of Abnormal Liver Chemistries Practice Guidance. (2017). https://www.aasld.org/practice-guidelines/evaluation-abnormal-liver-chemistries
  • MedlinePlus — Gamma-glutamyl transferase (GGT) test. (2024). https://medlineplus.gov/lab-tests/gamma-glutamyl-transferase-ggt-test/
  • ARUP Consult — Liver Disease Evaluation. (2024). https://arupconsult.com/content/liver-disease-evaluation
  • Mayo Clinic Laboratories — Gamma-Glutamyltransferase, Serum. (2023). https://www.mayocliniclabs.com/test-catalog/overview/6071
  • NHS — Liver function tests. (2023). https://www.nhs.uk/conditions/liver-function-test/
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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