APRI test

A simple score that uses AST and platelets to estimate liver scarring risk.

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APRI test
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Test Summary

Sample Type 
Blood
Required Blood
Analysis Type
Calculated index
Collection method
In person at the lab; at-home where available

Why test

APRI test

?

Clinicians use APRI to estimate liver scarring (fibrosis) and possible cirrhosis without a biopsy. It helps guide follow-up, such as elastography or ultrasound, and can track changes over time in chronic hepatitis or fatty liver. Results can support decisions about referral to a liver specialist. You can test this marker with Aniva across Germany and Finland.

What is

APRI test

?

Clinicians use APRI to estimate liver scarring (fibrosis) and possible cirrhosis without a biopsy. It helps guide follow-up, such as elastography or ultrasound, and can track changes over time in chronic hepatitis or fatty liver. Results can support decisions about referral to a liver specialist. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

APRI test

?

High: May suggest a higher chance of significant liver scarring. Your clinician may consider elastography, ultrasound, or other blood tests; review alcohol, medicines, and metabolic health.
Low: May indicate a low likelihood of advanced scarring. Continue routine monitoring if you have ongoing risks. Cutoffs vary by condition; your clinician interprets results with your history and other tests.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: When well; avoid heavy exercise or acute illness
  • Collection: In person at the lab; at-home where available
  • Typical volume:
  • Analysis: Calculated from AST and platelet count
  • Prep tips: Avoid strenuous exercise 24 hours prior; limit alcohol for 24–48 hours; list all medicines and supplements
  • Turnaround: Usually 1–3 business days

APRI test

is best interpreted with:

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APRI test

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Limits & interferences with

APRI test

:

Common factors include recent hard exercise or muscle injury (raises AST), alcohol, and some medicines or supplements that affect the liver or platelets. Acute illness, dehydration, and pregnancy can change results. Sample issues like hemolysis or platelet clumping may skew measurements.

Special situations: In pregnancy, chemotherapy, or acute hepatitis, confirm results with repeat testing and supportive tests (e.g., elastography) before decisions.

Questions about

APRI test

:

What does an APRI result mean? A higher score suggests a greater chance of significant liver scarring; a lower score suggests less. It is one part of the overall assessment.

Do I need to fast for APRI? No. Fasting is not required for AST or platelet count.

What can affect my APRI? Recent intense exercise, alcohol, some medicines or supplements, pregnancy, and acute illness can change AST or platelets.

How often should I check APRI? It depends on your condition and risk factors. Many people repeat it periodically to track changes.

How long do results take? Most labs report APRI within a few business days.

What should I discuss with my clinician? Share your medicines, alcohol use, viral hepatitis history, and metabolic risks. Ask if imaging or other scores are recommended.

Sources:

  • WHO — Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C infection. (2018). https://www.who.int/publications/i/item/9789241550345
  • WHO — Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection. (2015). https://www.who.int/publications/i/item/9789241549059
  • EASL — EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis. (2021). https://easl.eu/publication/easl-clinical-practice-guidelines-on-non-invasive-tests-for-evaluation-of-liver-disease-severity-and-prognosis/
  • ARUP Consult — Noninvasive Assessment of Liver Fibrosis and Cirrhosis. (2023). https://arupconsult.com/content/noninvasive-assessment-liver-fibrosis-cirrhosis
  • MedlinePlus — AST (Aspartate Aminotransferase) Blood Test. (2024). https://medlineplus.gov/lab-tests/ast-aspartate-aminotransferase-blood-test/
  • MedlinePlus — Platelet Count. (2024). https://medlineplus.gov/lab-tests/platelet-count/
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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