Total Protein

Total protein measures albumin and globulins in your blood, reflecting liver health, nutrition, and hydration.

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Total Protein
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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

Total Protein

?

Clinicians order total protein to check liver function, hydration status, and overall protein balance. It can help evaluate swelling, fatigue, weight changes, or signs of inflammation. Results often guide follow-up tests like albumin, A/G ratio, or protein electrophoresis. You can test this marker with Aniva across Germany and Finland.

What is

Total Protein

?

Clinicians order total protein to check liver function, hydration status, and overall protein balance. It can help evaluate swelling, fatigue, weight changes, or signs of inflammation. Results often guide follow-up tests like albumin, A/G ratio, or protein electrophoresis. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Total Protein

?

High: Often linked to dehydration or increased globulins from inflammation or immune activity. Some medicines or high-protein infusions can raise levels.
Low: May reflect poor intake, kidney protein loss, or reduced liver production. Overhydration and pregnancy can lower values. If results are unexpected, your clinician may review albumin, A/G ratio, or order protein electrophoresis.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Anytime; morning preferred for consistency
  • Collection: Venipuncture
  • Typical volume: 1 mL
  • Analysis: Serum
  • Prep tips: Stay well hydrated; avoid heavy exercise 24 hours before the draw
  • Turnaround: 1–2 business days

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Total Protein

with Aniva

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Total Protein
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Limits & interferences with

Total Protein

:

Common factors that may affect results include hydration status, recent IV fluids, prolonged tourniquet use, and posture during the draw. Strenuous exercise, acute illness, pregnancy, and recent high-protein infusions can shift values. Some medicines (such as corticosteroids or estrogens) and heavy alcohol use may also influence levels.

Special situations (when to confirm or adjust): repeat testing if you were acutely ill, dehydrated, or after large fluid changes; discuss timing if pregnant or receiving monoclonal antibody therapy.

Questions about

Total Protein

:

What does my total protein result mean? It reflects the combined levels of albumin and globulins. Your clinician will interpret it alongside albumin, A/G ratio, and other liver tests.

Do I need to fast for this test? No. Eating does not meaningfully change total protein for most people.

What can affect my results? Dehydration, IV fluids, pregnancy, intense exercise, acute illness, and some medicines can shift values.

How often should I test total protein? Usually during routine checkups or when monitoring known issues. Follow your clinician’s advice.

How long do results take? Most labs report results within 1–2 business days.

What should I discuss with my clinician? Share symptoms, hydration status, medications, and supplements. Ask if follow-up tests like albumin or protein electrophoresis are needed.

Sources:

  • MedlinePlus — Total protein and albumin/globulin (A/G) ratio. (2024). https://medlineplus.gov/lab-tests/total-protein-and-albumin-globulin-a-g-ratio/
  • Mayo Clinic Laboratories — Protein, Total, Serum. (2023). https://www.mayocliniclabs.com/test-catalog/overview/8326
  • ARUP Consult — Comprehensive Metabolic Panel. (2024). https://arupconsult.com/ati/comprehensive-metabolic-panel
  • UCSF Health — Total protein blood test. (2023). https://www.ucsfhealth.org/medical-tests/total-protein
  • Pathology Tests Explained (RCPA) — Total Protein. (2022). https://pathologytestsexplained.org.au/tests/total-protein
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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