CRP/HDL

A simple ratio comparing inflammation (CRP) to good HDL cholesterol to add heart-health context.

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CRP/HDL
 test

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Test Summary

Sample Type 
Blood
Required Blood
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

CRP/HDL

?

CRP/HDL can add context to heart and metabolic risk, especially when hs-CRP or cholesterol results seem mixed. It helps track changes from diet, exercise, weight, and medicines that affect inflammation and HDL. It is most useful alongside your lipid panel and standard risk scores. You can test this marker with Aniva across Germany and Finland.

What is

CRP/HDL

?

CRP/HDL can add context to heart and metabolic risk, especially when hs-CRP or cholesterol results seem mixed. It helps track changes from diet, exercise, weight, and medicines that affect inflammation and HDL. It is most useful alongside your lipid panel and standard risk scores. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

CRP/HDL

?

High: Points to more inflammation compared with your HDL level. Review lifestyle basics and discuss other risk markers with your clinician.
Low: Points to less inflammation relative to HDL. Keep healthy habits and watch trends over time. This ratio is not guideline-endorsed; no standardized cutoffs. Read it with hs-CRP, HDL cholesterol, LDL cholesterol, and ApoB, and recheck when you are well.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: When well, not during acute illness; morning preferred
  • Collection: In person at the lab; at-home where available
  • Typical volume:
  • Analysis: Serum
  • Prep tips: Avoid strenuous exercise and alcohol for 24 hours; tell the lab about medicines and supplements
  • Turnaround: 1-3 working days

Track your

CRP/HDL

with Aniva

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CRP/HDL
 test

Limits & interferences with

CRP/HDL

:

Common factors that can skew results include acute infection, recent injury, surgery, or vaccination; strenuous exercise; smoking; heavy alcohol; dehydration; and pregnancy. Medicines and supplements may shift values: statins, fibrates, niacin, omega-3s, hormone therapy, corticosteroids, and NSAIDs can lower inflammation or alter HDL. Large weight changes, poor sleep, and chronic inflammatory conditions also affect results.

Special situations: if you are sick, recently vaccinated, postpartum, in an autoimmune flare, or starting/stopping lipid-lowering therapy, confirm with a repeat test when stable.

Questions about

CRP/HDL

:

What does a high or low CRP/HDL mean? A higher ratio points to more inflammation relative to your HDL level. A lower ratio suggests less inflammation compared with your HDL.

Do I need to fast for this test? Fasting is not required. If your clinician asked for a fasting lipid panel, follow their instructions.

What can affect my result? Illness, recent vaccines, hard workouts, smoking, alcohol, dehydration, pregnancy, and medicines like statins or steroids can shift results.

How often should I test it? Many people recheck every few months when adjusting lifestyle or treatment. Your clinician can suggest a timing that fits your risk.

How long do results take? Most labs report results in about 1-3 working days.

What should I discuss with my clinician? Review your hs-CRP, full lipid panel, family history, symptoms, and habits. Ask how this ratio fits your overall heart-risk plan.

Sources:

  • ACC/AHA — 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease. (2019). https://www.acc.org/Latest-in-Cardiology/ten-points-to-remember/2019/03/07/16/00/2019-prev-guideline
  • ACC/AHA — 2018 Guideline on the Management of Blood Cholesterol. (2018). https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2018/11/10/19/27/2018-cholesterol-guideline
  • ESC/EAS — 2019 ESC/EAS Guidelines for the management of dyslipidaemias. (2019). https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Dyslipidaemias-Management-of
  • MedlinePlus — C-reactive protein (CRP) test. (2022). https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/
  • MedlinePlus — HDL cholesterol test. (2023). https://medlineplus.gov/lab-tests/hdl-cholesterol-test/
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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